Cost-effectiveness and budget effect of pre-exposure prophylaxis for HIV-1 prevention in Germany from 2018 to 2058
Our objective was to assess cost-effectiveness and costs of introducing PrEP in Germany.We calibrated a deterministic mathematical model to the human immunodeficiency virus (HIV)epidemic among MSM in Germany. PrEP was targeted to 30% of high-risk MSM. It was assumed that PrEP
reduces the risk of HIV infection by 85%. Costs were calculated from a ...
Delays in diagnosis of HIV and initiation of antiretroviral therapy (ART) for infants significantly increase early infant morbidity and mortality. By contrast, innovations in early infant HIV diagnostics and improvements in turnaround times could reduce infant morbidity and mortality.
Early treatment of acute hepatitis C infection is cost-effective in HIV-infected men-whohave- sex-with-men
Treatment of hepatitis C virus infections (HCV) with direct acting antivirals (DAA) can prevent new infections since cured individuals cannot transmit HCV. However, as DAAs are expensive, many countries defer treatment to advances stages of fibrosis, which results in ongoing transmission. We assessed the epidemiological impact and cost-effectiveness oftreatment initiation in different stages of infection ...
The Health Economics and Epidemiology Research Office (HE2RO) of the University of the Witwatersrand seeks a dynamic, enthusiastic, and self-motivated quantitative senior researcher with experience in mathematical disease, cost, and/or health systems modelling to be part of our health economics and epidemiology research portfolios. Research in these portfolios focus on the impact, costs, cost-effectiveness, and ...
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HE2RO has been awarded a new 5-year Co-operative Agreement from USAID. This new program, the HIV/AIDS Economics and Research Activity, called EVIDENCE will run...
HE2RO has been approved to be a HBNU site for the Fogarty Global Health Training Program. The program provides opportunities to generate a new...
HE2RO and BU are pleased to announce a new project focusing on differentiated models of HIV treatment delivery: AMBIT.