HIV treatment outcomes in South Africa: fixed-dose combination vs. traditional multi-pill ART

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Currently, there are a limited number of studies focusing specifically on the effects of active ARV drugs administered as separate pills compared to those same active drugs administered in a fixed dose combination. Thus the current study helps fill a critical gap in literature. Our results suggest that under programmatic conditions, FDCs achieve similar outcomes in terms of attrition and virology suppression compared to a multi-pill regimen. However, FDCs may have an important role to play in supporting patient monitoring and adherence through improved clinic attendance via medical visits.

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