Predictors of switch to and early outcomes on third-line antiretroviral therapy at a large public-sector clinic in Johannesburg, South Africa

By  Denise Evans  Kamban Hirasen  Ribka Berhanu  Given Malete  Prudence Ive, David Spencer, Sharlaa Badal-Faesen  Professor Ian Sanne  Matthew Fox  |  | 

While efficacy data exist, there are limited data on the outcomes of patients on third-line antiretroviral therapy (ART) in sub-Saharan Africa in actual practice. Being able to identify predictors of switch to third-line ART will be essential for planning for future need. We identify predictors of switch to third-line ART among patients with significant viraemia on a protease inhibitor (PI)-based second-line ART regimen. Additionally, we describe characteristics of all patients on third-line at a large public sector HIV clinic and present their early outcomes.

Publication details

AIDS Research and Therapy
#15
2018
10
PDF
https://www.ncbi.nlm.nih.gov/pubmed/29636106