All Policy Briefs

APPLYING MACHINE LEARNING TO LABORATORY DATA: PREDICTING SUPPRESSION OF NEXT HIV VIRAL LOAD IN SOUTH AFRICA

During 2018, South Africa was estimated to have more than seven million people living with HIV1, representing the largest single country epidemic2 and treatment program. 3 In September 2016, the National Department of Health revised its treatment guidelines to extend the availability of ART to all people living with HIV, irrespective of CD4 cell count and stage of disease3. This policy, widely referred to as “treat all” or “universal test and treat” (UTT) holds promise to offer 

THE SLATE ALGORITHM FOR SAME-DAY HIV TREATMENT INITIATION: RESULTS OF THE SLATE TRIAL IN SOUTH AFRICA AND KENYA

The World Health Organization recommends "sameday" initiation of antiretroviral therapy (ART) for HIV patients eligible and ready1. This recommendation has been adopted by both South Africa2 and Kenya3. Identifying efficient, safe, and feasible procedures for determining same-day eligibility and readiness is now a priority. The WHO guidelines cited evidence from clinical trials suggesting that offering treatment to patients at their first clinical encounter has the potential to increase 

MAKING BUDGETING WORK: REFLECTIONS FROM THE FINANCIAL CAPACITY BUILDING FOR PROVINCES (FINCAP) PROJECT IN SOUTH AFRICA

The Financial Capacity Building for Provinces (FINCAP) project, run in partnership by the Centre for Economic Governance and Accountability in Africa (CEGAA) and the Health Economics and Epidemiology Research Office (HE2RO), focuses on providing capacity building and technical support to HIV, STI and TB (HAST) programme and finance managers in provincial departments of health in South Africa. The intervention was designed to improve budget planning, costing, expenditure tracking and reporting 

BASly – AN AUTOMATED TOOL FOR ANALYSING HIV and TB RELATED EXPENDITURE

The Basic Accounting System (BAS) caters for the South African government’s basic accounting needs. It is the general ledger where all financial transactions are recorded and classified in accordance with the Standard Chart of Accounts (SCoA) system. Transactions are initially recorded in sub-systems i.e. payroll system, inventory and asset management, pharmaceuticals and payment of utilities. Measures are taken to ensure that information in the sub-systems matches transactions captured in 

Budget execution of the comprehensive HIV and AIDS conditional grant: An analysis of expenditure and performance: HE²RO Policy Brief Number 30

South Africa’s government-wide expenditure on HIV/AIDS programmes is estimated to have almost doubled over the past five financial years from R10.6 billion in 2012/13 to R20.3 billion in 2017/18.1* The majority of this expenditure (85.2% in 2017/18) is funded through the HIV, TB, Malaria and Community Outreach Grant, which is a ring-fenced conditional grant (CG) allocated via the National Department of Health (NDOH) to provincial health budgets. The HIV/AIDS component of this grant is one of 

USING PRIVATE MEDICAL SCHEME DATA TO ESTIMATE SOUTH AFRICA’S HIV CARE AND TREATMENT BURDEN BY GEOGRAPHIC AREA

In 2017, South Africa had 7.2 million people living with HIV, of whom 61% were on antiretroviral therapy (UNAIDS 2018). While HIV treatment in the public sector is well documented through national electronic medical record systems, such as Tier.Net, DHIS, and the NHLS data warehouse, little is known about the role of the private sector in HIV treatment service delivery (Awsumb et al, IAS 2017). In particular, there are no published geographic data describing the HIV disease burden amongst 

Breast cancer screening, diagnostic and treatment services and integration with HIV-related care in Sub-Saharan Africa: Results from an electronic survey

There is very little data on the availability of breast care screening and treatment services in sub-Saharan Africa, and almost no information on integration of HIV and breast care services in this setting. In this study we assessed the availability of comprehensive breast care services and their integration (or not) with HIV care and treatment services in sub-Saharan Africa, with a special focus on South Africa which has placed an emphasis on integration of HIV and SRH care in its public 

Syndromic management versus point-of-care, and lab based testing for Chlamydia and Gonorrhoea: A cost comparison

In this analysis, syndromic management was the least costly option. It requires skilled personnel but minimal supplies, equipment, and medication.Despite higher costs per case tested, the WHO has recommended etiological testing in countries that can afford it as part of its 2016-2021 strategy for global STI control.3 The added cost of etiological testing is possibly less than that of syndromic management if one considers the costs of caring for the many short- and long-term sequelae of 

Syndromic Management vs Point-of-Care, and Lab Based Testing for Chlamydia and Gonorrhoea: a Cost Comparison

Despite higher costs per case tested, the WHO has recommended etiological testing in countries that can afford it as part of its 2016-2021 strategy for global STI control.3The added cost of etiological testing is possibly less than that of syndromic management if one considers the costs of caring for the many short- and long-term sequelae of untreated STIs, including ectopic pregnancy, pelvic inflammatory disease, and infertility in women, and additional complications for newborns. However, 

Frequent Mobility among Postpartum Women: Implications for HIV Treatment and Care

We found frequent movement between facilities, as well as frequent log-distance travel during the postpartum period. The movement between facilities results in an overestimation of true LTFU. A concerted effort to synchronise data between facilities in real-time is needed both for quality of patient care and program 

Does distance to clinic affect utilization of HIV care and treatment services

We assessed the relationship between distance to clinic and progression through the HIV care cascade. We have two key findings. First, distance matters but only for women. Second, for women, distance affected linkage to care, but was not associated with later transitions in the care cascade. It is possible that distance is a less important barrier once people find out their HIV status, learn about treatment, and overcome the hurdle of their first clinic 

Drug side effects and retention on HIV treatment: a prospective cohort study assessing the implementation of Tenofovir in South Africa and Zambia

With its recommendations that all patients initiate Tenofovir, WHO anticipated improved adherence and reduced lost to follow-up, with implications for long health outcomes such as CD4 recovery, viral suppression and survival. We show that the guideline change replacing Stavudine with Tenofovir in first-line ART improved retention in care and reduced single-drug