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Multimonth dispensing of up to 6 months of antiretroviral therapy in Malawi and Zambia (INTERVAL): a clusterrandomised, non-blinded, non-inferiority trial
Background: Facility-based, multimonth dispensing of antiretroviral therapy (ART) for HIV could reduce burdens on patients and providers and improve retention in care. We assessed whether 6-monthly ART dispensing was non-inferior to standard of care and 3-monthly ART dispensing. Methods: We did a pragmatic, cluster-randomised, unblinded, non-inferiority trial (INTERVAL) at 30 health facilities in ...
Economic evaluation of differentiated service delivery models for HIV treatment in Lesotho: costs to providers and patients
Introduction: Lesotho, the country with the second-highest HIV/AIDS prevalence (23.6%) in the world, has made considerable progress towards achieving the “95-95-95” UNAIDS targets, but recent success in improving treatment access to all known HIV positive individuals has severely strained existing healthcare infrastructure, financial and human resources. Lesotho also faces the challenge of a ...
Cost-effectiveness analysis of flucytosine as induction therapy in the treatment of cryptococcal meningitis in HIV-infected adults in South Africa
Background: Cryptococcal meningitis in HIV-infected patients in sub-Saharan Africa accounts for three-quarters of the global cases and 135,000 deaths per annum. Current treatment includes the use of fluconazole and amphotericin B. Recent evidence has shown that the synergistic use of flucytosine improves efficacy and reduces toxicity, however affordability and availability has hampered access ...
We seek a dynamic, enthusiastic, and self-motivated quantitative senior researcher to be part of our health economics research and implementation science portfolio. This portfolio focuses on the costs, cost-effectiveness, and benefits of healthcare interventions, health financing and health systems, and other priority public health challenges, with opportunities for both primary data collection and mathematical modeling. ...
- 01 JAN Indlela Request for Expressions of Interest: Virtual Behavioural Insights Test (BIT) Development Workshop Series
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We are pleased to announce that we are now able to share the reports on the projections of the National Covid-19 Epi Model to which...
HE2RO has been awarded a new 5-year Co-operative Agreement from USAID. This new program, the HIV/AIDS Economics and Research Activity, called EVIDENCE will run...