Oral diseases, even in moderate stages of severity can impact quality of life in patients due to the accompanying pain, lengthy duration of treatment, inability to eat or speak with full functionality and aesthetic decline and when occurring among those who are HIV positive might also impact their ability to take their medication correctly. When combined with co-morbidities and other risk factors, disease progression is often rapid if not diagnosed and treated promptly. Malignancies also increase the risk for mortality. For this pilot study we aim to estimate prevalence of oral disease, pre-malignancies and malignancies by HIV status among adults seeking dental care at a tertiary hospital in South Africa; and to understand how oral disease progression differs by HIV status, for which minimal data in the African region currently exists
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