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Despite ongoing challenges as the COVID-19 pandemic continued, 2021 saw achievements in progress and productivity across several projects with new collaborations and exciting opportunities for studies in key public health areas. The Health Economics and Epidemiology Research Office (HE2RO) continued to expand its research and evaluation projects in South Africa and its neighbouring countries. The Sentinel protocol for the Bill and Melinda Gates Foundation (BMGF) funded Alternative Models of ART Delivery: Optimising the Benefits (AMBIT) study was approved in all three focus countries (Malawi, South Africa and Zambia) and field work resumed as COVID-19 restrictions were lifted. Along with colleagues at the Department of Global Health, Boston University School of Public Health, HE2RO was successfully awarded the Retain6 grant through BMGF and the National Institutes of Health (NIH) funded CETA study both of which commenced project work in the last quarter of 2021.

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