Recent Publications

Applying machine learning and predictive modeling to retention and viral suppression in South African HIV treatment cohorts

HIV treatment programs face challenges in identifying patients at risk for loss-to-follow-up and uncontrolled viremia. We applied predictive machine learning algorithms to anonymised, patientlevel HIV programmatic data from two districts in South Africa, 2016–2018. We developed patient risk scores for two outcomes: (1) visit attendance≤ 28 days of the next scheduled clinic visit and (2) suppression of the next HIV viral load (VL). Demographic, clinical, behavioral and laboratory data were 

Costs of seasonal influenza vaccination in South Africa

Abstract Background: Influenza accounts for a substantial number of deaths and hospitalisations annually in South Africa. To address this disease burden, the South African National Department of Health introduced a trivalent inactivated influenza vaccination programme in 2010. Methods: We adapted and populated the WHO Seasonal Influenza Immunization Costing Tool (WHO SIICT) with country-specific data to estimate the cost of the influenza vaccination programme in South Africa. Data were 

HERO BU Presentation AIDS 2022

The 24th International AIDS Conference will commence on the 29th of July and ending on the 2nd of August. We will be presenting on various topics. Access our  HE2RO BU Presentation Flyer AIDS 2022 by clicking on the PDF file 

TB economics: A decade of research

This review assess HE2RO's contribution to the body of evidence on the cost of providing services for TB in South Africa and highlights gaps to inform future research efforts. What did we do? We reviewed and summarised abstracts, presentations, and publications from HE2RO authors which estimated the cost of TB services in the South African National TB Control Program and were disseminated between January 2010 and June 

Integration of tuberculosis and mental health care services

Summary The physical, psychological, social and economic burden of TB on the patient before, during and even after TB treatment is significant.  Routine screening and effective management of comorbid depression and anxiety in TB patients should be incorporated into TB programmes using a more holistic approach to TB care. Integrating psycho-socio-economic support interventions can add significant value to TB control through improvements in treatment success rates and reductions in 

How soon should patients be eligible for differentiated service delivery models for antiretroviral treatment?

Attrition from HIV  treatment (ART) is highest during patients' firsts  months after initiation. Although ≥6 months on ART is an eligibility criterion for most differentiated service delivery (DSD) model guidelines, some patients enroll earlier. We used routinely-collected data on DSD models in Zambia to evaluate loss to follow-up (LTFU) comparing patient enrolling in DSD models early vs those who did so later (>6 

“I was scared dating… who would take me with my status?”- Living with HIV in the UTT era in Johannesburg, South Africa

Despite South Africa’s rollout of Universal Test-and-Treat (UTT) in 2016, many people living with HIV (PLHIV) still experience gaps in ART uptake, adherence, and retention. We sought to understand how PLHIV perceive their HIV status in the UTT era, if there are any challenges, and how their experiences differ from individuals diagnosed with HIV at earlier stages of the 

Does differentiated service delivery for HIV treatment change healthcare providers workload? Provider views from Malawi, South Africa, and Zambia

Differentiated service delivery (DSD) models aim to make delivery of HIV treatment more efficient, reduce the burden on healthcare providers, decongest clinics, and improve quality of care and/or increase clinic capacity. Although many countries are implementing DSD models, there is limited evidence on how they affect providers’ 

Talking about Treatment-as-Prevention and U=U: patient needs and health worker perspectives

People who are virally-suppressed cannot transmit HIV sexually. While the science of HIV treatment- as-prevention (TasP) is clear, this message has not been disseminated widely in sub-Saharan Africa, limiting its value in motivating treatment uptake, adherence, and retention HIV care. We sought to understand the TasP communication needs of persons living with HIV (PLHIV) and barriers and facilitators to TasP communication among health care workers in South