Post-tuberculosis lung health: perspectives from the First International Symposium

By B. W. Allwood, M. M. van der Zalm, A. F. S. Amaral, A. Byrne, S. Datta, U. Egere, C. A. Evans  Dr. Denise Evans  D. M Gray, G. Hoddinott, O. Ivanova, R. Jones, G. Makanda, F. M. Marx, J. Meghji, S. Mpagama, J. G. Pasipanodya, A. Rachow, I. Schoeman, J. Shaw, C. Stek, S. van Kampen, D. von Delft, N. F. Walker, R. S. Wallis, K. Mortimer  |  | 

ALTHOUGH CURABLE, TB frequently leaves the individual with chronic physical and psycho-social impairment, but these consequences have been largely neglected. The 1st International Post-Tuberculosis Symposium (Stellenbosch, South Africa) was held to discuss priorities and gaps in addressing this issue. A barrier to
progress has been the varied terminology and nomenclature, so the Delphi process was used to achieve consensus
on definitions. Lack of sufficient evidence hampered definitive recommendations in most domains, including
prevention and treatment of post-TB lung disease (PTLD), but the discussions clarified the research needed.
A consensus was reached on a toolkit for future PTLD measurement and on PTLD patterns to be considered.
The importance of extra-pulmonary consequences and progressive impairment throughout the life-course was
identified, including TB recurrence and increased mortality. Patient advocates emphasised the need to address
the psychological and social impacts post TB and called for clinical guidance. More generally, there is an urgent
need for increased awareness and research into post-TB complications.

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