Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa

By Morna Cornell, Anna Grimsrud, Lara Fairall  Dr. Matthew Fox  Gilles van Cutsem, Janet Giddy, Robin Wood  Hans Prozesky, Lerato Mohapi, Claire Graber  Matthias Egger, Andrew Boulle, Landon Myer  |  | 


South Africa has the largest ART programme in the world [1]. Between 2004 (the start of the national ART programme) and 2007, an estimated 370,000 people initiated treatment in the public sector [2]. But despite the scope and rapid growth of this programme there are no data on programme outcomes at a national level. The International Epidemiologic Databases to Evaluate AIDS collaboration of Southern Africa (IeDEA-SA) has assembled a series of HIV treatment cohorts from across the country that include approximately 10% of all adults who initiated public sector ART in South Africa by the end of 2007. The aim of this paper is to describe trends in mortality, loss to follow-up (LTFU) and programme retention of these adult patients over the first 5 years of the country’s national ART programme.

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