All Abstracts

HERO BU Presentation AIDS 2022

The 24th International AIDS Conference will commence on the 29th of July and ending on the 2nd of August. We will be presenting on various topics. Access our  HE2RO BU Presentation Flyer AIDS 2022 by clicking on the PDF file 

How soon should patients be eligible for differentiated service delivery models for antiretroviral treatment?

Attrition from HIV  treatment (ART) is highest during patients' firsts  months after initiation. Although ≥6 months on ART is an eligibility criterion for most differentiated service delivery (DSD) model guidelines, some patients enroll earlier. We used routinely-collected data on DSD models in Zambia to evaluate loss to follow-up (LTFU) comparing patient enrolling in DSD models early vs those who did so later (>6 

“I was scared dating… who would take me with my status?”- Living with HIV in the UTT era in Johannesburg, South Africa

Despite South Africa’s rollout of Universal Test-and-Treat (UTT) in 2016, many people living with HIV (PLHIV) still experience gaps in ART uptake, adherence, and retention. We sought to understand how PLHIV perceive their HIV status in the UTT era, if there are any challenges, and how their experiences differ from individuals diagnosed with HIV at earlier stages of the 

Talking about Treatment-as-Prevention and U=U: patient needs and health worker perspectives

People who are virally-suppressed cannot transmit HIV sexually. While the science of HIV treatment- as-prevention (TasP) is clear, this message has not been disseminated widely in sub-Saharan Africa, limiting its value in motivating treatment uptake, adherence, and retention HIV care. We sought to understand the TasP communication needs of persons living with HIV (PLHIV) and barriers and facilitators to TasP communication among health care workers in South 

Anticipated stigma among recently diagnosed HIV clients in the UTT era in Johannesburg, South Africa

Anticipated stigma – the fear that HIV diagnosis and status disclosure could have negative social implications – may adversely affect engagement with HIV care and treatment, despite universal eligibility for treatment under universal test-and-treat (UTT). We aimed to determine prevalence and predictors of anticipated stigma among newly HIV diagnosed individuals under the UTT policy in Johannesburg, South 

How do nurses spend their time? A time and motion analysis in the context of differentiated service delivery at primary public healthcare facilities in South Africa

Among other benefits, differentiated service delivery (DSD) models are expected to reduce the time that clinicians spend with established ART clients enrolled in DSD models and thus potentially increase available provider time for non-DSD ART and non-ART clients. The actual use of provider time after DSD model implementation has not been reported. We measured healthcare provider time utilization in the context of DSD model implementation in South 

The relative cost-effectiveness of long-acting injectable cabotegravir versus oral pre-exposure prophylaxis: a modelled economic evaluation and threshold analysis in South Africa based on the HPTN 083 and 084 trials

Long-acting cabotegravir (CAB-LA), administered 2-monthly, is more effective at preventing HIV infection than daily oral tenofovir (TDF)/emtricitabine (FTC), but its cost-effectiveness in a high-prevalence setting is not known. We estimated the cost-effectiveness of CAB-LA compared to TDF/FTC in South Africa and determined the threshold price at which CAB-LA is as cost-effective as 

Observed time to HIV treatment initiation in the era of same-day initiation in Malawi, South Africa, and Zambia

Since 2017 global guidelines have recommended “same-day initiation” (SDI) of antiretroviral treatment (ART) for patients considered ready for treatment on the day of HIV diagnosis. Many countries in sub-Saharan Africa have incorporated a SDI option into national guidelines, but uptake of SDI is not well documented. We estimated average time to ART initiation at 12 public healthcare facilities in Malawi, 5 in South Africa, and 12 in