All Presentations

AIDS 2012: CD4 criteria improves the sensitivity of a clinical algorithm developed to identify viral failure in HIV-positive patients on first-line antiretroviral therapy

Abstract Background: Routine viral load monitoring of patients on antiretroviral therapy (ART) is neither affordable nor available in most resource-limited settings. We used data from an electronic patient management system to develop an algorithm to identify patients at risk of viral failure using a combination of accessible and inexpensive markers. Methods: We analyzed data from HIV-positive adults initiated on ART at Themba Lethu Clinic, South Africa between April 2004-February 2010. Viral 

The impact of antiretroviral therapy on quality of life and economic outcomes for South African patients: five-year follow-up

Abstract Background: The rapid expansion of antiretroviral therapy (ART) programs in resource-constrained countries in the previous decade has led to large numbers of patients reaching ≥5 years on ART, but little evidence exists about long-term economic outcomes. We report the effect of ART on symptoms, general health, ability to perform normal activities, and employment among patients in South Africa during the first five years on treatment. Methods: A cohort of 1065 adult South African 

CD4 criteria improves the sensitivity of a clinical algorithm developed to identify viral failure in HIV-positive patients on first-line antiretroviral therapy

Abstract Background: Routine viral load monitoring of patients on antiretroviral therapy (ART) is neither affordable nor available in most resource-limited settings. We used data from an electronic patient management system to develop an algorithm to identify patients at risk of viral failure using a combination of accessible and inexpensive markers. Methods: We analyzed data from HIV-positive adults initiated on ART at Themba Lethu Clinic, South Africa between April 2004-February 2010.