Dr Sophie Pascoe [Principal Researcher - Epidemiology ]

T: (0) 10 001 2661  
Dr Sophie Pascoe

Sophie Pascoe is an Epidemiologist and Principal Researcher at the Health Economics and Epidemiology Research Office and holds a joint appointment in the School of Clinical Medicine at the University of the Witwatersrand, Johannesburg. She has been resident in South Africa since 2004 and joined HE2RO in 2015. She holds a Masters and Doctorate degree in Epidemiology from the London School of Hygiene and Tropical Medicine (LSHTM). Sophie has over 15 years of experience in HIV and sexual and reproductive health research, implementation of randomised control trials, and operational research evaluating health systems strengthening interventions in the region. Currently her research focuses on linkage to care, treatment adherence and retention in care among people living with HIV and the implementation of differentiated models of care as well as exploring the preferences of young people for HIV and contraceptive services. She was the local Principal Investigator for a large collaborative study with the World Bank, South African National Department of Health (NDoH) and Boston University evaluating the NDoH’s National Adherence Guidelines for Chronic Diseases (ENHANCE study). Currently she is the Principle Investigator for two large USAID funded studies exploring the preferences of high school students for HIV and contraceptive services and evaluating viral load monitoring and reporting at primary healthcare sites in South Africa. She is also the local PI for the AMBIT Study (Alternative Models of ART Delivery: Optimising the Benefits) funded by the Bill and Melinda Gates Foundation. In addition, Sophie is a Deputy Editor for the Journal of the International AIDS Society, frequently reviews manuscripts for both local and international journals in the HIV filed and has authored and co-authored 30 peer-reviewed articles in several international journals (Google scholar h-index of 21 and 1496 citations (https://scholar.google.com/citations?hl=en&user=vEmnzxkAAAAJ).


  • AMBIT: Alternative Models of ART Delivery – Optimizing the Benefits

    AMBIT is a 2.5-year research and evaluation project in sub-Saharan Africa supported by the Bill & Melinda Gates Foundation and implemented by the Boston University School of Public Health in the U.S., the Health Economics and Epidemiology Research Office (HE2RO) in South Africa, and other local partners. The project, launched in September 2018, will include data synthesis, data collection, data analysis, and modeling activities aimed at generating information for near- and long-term 
  • Explore Students’ and Other Stakeholders’ Preferences for Students’ Access to SRH and HIV Services, Including in Schools

    South Africa recently initiated the Integrated School Health Program (ISHP), a progressive program grounded in the School Health Policy and Implementation Guidelines established in 2003. The ISHP includes screening for a range of health services in select schools. There is debate regarding whether to include provision of HIV-related services and SRH services, including contraception, in schools through the ISHP. We aim to explore the preferences of learners, parents and teachers regarding the 
  • Adult Treatment Outcomes and Opportunistic Infections

    As the HIV epidemic matured in South Africa and the national treatment programme reached 10 years since inception, the team at HE2RO has used longitudinal patient databases to evaluate treatment outcomes among adults initiating ART. We consider diverse factors that may influence the effect of ART and also the impact of changing national guidelines in an on-going